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Blink 3 von 12 - Eine kurze Geschichte der Menschheit
von Yuval Noah Harari
The True Tale of America’s Opiate Epidemic
The opiate crisis is being felt all over the United States – but it didn’t come out of nowhere. It’s a been a slow process, the foundations of which were laid back in the early 1980s.
In 1984, the drug company Purdue released a new product called MS Contin. It was a time-release morphine pill designed for treating pain in patients who were dying or who had just been released from surgery.
It was highly successful, so much so that the company released a similar drug in 1996. This new drug had oxycodone as its active ingredient, rather than MS Contin’s morphine. Oxycodone is an opium derivative not dissimilar to heroin, and once more Purdue used its time-release coating formula. The name of this pill was OxyContin.
The FDA approved OxyContin in 1995, as they believed Purdue’s big claim about the pill: supposedly, their time-release coating would limit addiction by preventing the sorts of rapid highs and lows usually associated with opiates.
The consequences of this decision were serious: now Purdue could market OxyContin with a unique safety label that stated the drug had less potential for abuse than other painkilling drugs on the market.
It was this claim that became the cornerstone of OxyContin’s marketing. This wonder drug would purportedly be the only painkiller a doctor would ever need to prescribe. It was to be an almost risk-free solution to chronic pain; unlike other opiates doctors had been prescribing for pain, this new drug had been shown to be addictive in less than 1 percent of patients.
But there was a very specific reason these rates of addiction were so low: MS Contin was being used in carefully controlled hospital conditions. Conversely, OxyContin was marketed to doctors outside hospitals. And these doctors were used to dealing with chronic pain in their patients by prescribing opiates.
Now, these old opiates were quite weak, their dosages were small, and they contained agents such as acetaminophen or Tylenol designed to prevent abuse.
Oxycontin was different. It contained large doses of oxycodone and was only deemed safe because of the special time-release coating designed to supply the active ingredient over a long period.
Purdue soon began pushing its new product. Its representatives visited doctors several times a year and took them out to lavish lunches, attempting to drive home the merits of the time-release coating and how it ensured addiction was not an issue.
It didn’t stop there: mountains of OxyContin merchandise and medical seminars at luxurious resorts were quite the norm.
And it was a success: Purdue’s sales tripled. In fact, bonuses for sales rose from $1 million in 1996 to a whopping $40 million in 2001. By 2003, OxyContin was predominantly being prescribed by primary care doctors with very little pain management training. Purdue had successfully transformed the entire industry: prescribing for pain had become the norm, not the exception.
Dreamland (2015) tells the story of how the opiate crisis in the United States went from being a problem only among social outcasts and the urban poor to one of the leading causes of accidental deaths in the country. The background and science of the crisis are rooted in socioeconomic factors that are distinctly American.
OxyContin prescriptions for chronic pain rose from 670,000 in 1997 to 6.2 million in 2002.
Ich bin begeistert. Ich liebe Bücher aber durch zwei kleine Kinder komme ich einfach nicht zum Lesen. Und ja, viele Bücher haben viel bla bla und die Quintessenz ist eigentlich ein Bruchteil.
Genau dafür ist Blinkist total genial! Es wird auf das Wesentliche reduziert, die Blinks sind gut verständlich, gut zusammengefasst und auch hörbar! Das ist super. 80 Euro für ein ganzes Jahr klingt viel, aber dafür unbegrenzt Zugriff auf 3000 Bücher. Und dieses Wissen und die Zeitersparnis ist unbezahlbar.
Extrem empfehlenswert. Statt sinnlos im Facebook zu scrollen höre ich jetzt täglich zwischen 3-4 "Bücher". Bei manchen wird schnelle klar, dass der Kauf unnötig ist, da schon das wichtigste zusammen gefasst wurde..bei anderen macht es Lust doch das Buch selbständig zu lesen. Wirklich toll
Einer der besten, bequemsten und sinnvollsten Apps die auf ein Handy gehören. Jeden morgen 15-20 Minuten für die eigene Weiterbildung/Entwicklung oder Wissen.
Viele tolle Bücher, auf deren Kernaussagen reduziert- präzise und ansprechend zusammengefasst. Endlich habe ich das Gefühl, Zeit für Bücher zu finden, für die ich sonst keine Zeit habe.
Hol dir mit Blinkist die besten Erkenntnisse aus mehr als 7.000 Sachbüchern und Podcasts. In 15 Minuten lesen oder anhören!
Jetzt kostenlos testenBlink 3 von 12 - Eine kurze Geschichte der Menschheit
von Yuval Noah Harari