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Zusammenfassung von Ending Aging

Name: Ending Aging
Rating: 3.3 (121 reviews)
Author: Aubrey de Grey

Aubrey de Grey

The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

3.3 (121 Bewertungen)

18 Min.

Kurz zusammengefasst

'Ending Aging' by Aubrey de Grey is a groundbreaking book that presents a roadmap for ending the aging process. Through radical life extension techniques, it aims to give people a radically increased chance to live healthy and longer lives.

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Ending Aging
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What’s in it for me? Discover what it takes to avoid aging and foil death.

Most of us have witnessed our grandparents getting old. We’ve seen how their skin grew paler and thinner, how they suddenly weren’t as mobile anymore and how their memory began to deteriorate. Aging is a difficult and delicate matter.

So, who wouldn’t want to live forever? Or at least double one’s lifespan? Most people would.

Drawing from his own intense wish to end aging – and his scientific knowledge – the author provides a thorough introduction to the seven-step program that he has developed as a means against aging.

In these blinks, you’ll discover

why free radicals should be avoided if you want to live longer;
why graves aren’t glowing in the dark; and
how to eliminate cancer.

Aging is a part of every human life, or is it?

As the saying goes, two things are unavoidable in life: death and taxes. While it’s true that there isn’t much we can do to keep the government from taking a chunk out of our paycheck, we are becoming better at delaying death.

We’ve long accepted aging as an unavoidable, though unpleasant, fact of life. Most people don’t think there’s much sense in worrying about something we have no control over. Why waste time trying to prevent the inevitable? After all, how can you enjoy life if you’re worrying about an unsolvable problem?

There are also those who believe that solving the problem of aging could be a bad thing; there are concerns that such a solution would contribute to overpopulation, or that the solution would only be available to the extremely wealthy.

But there are many – the author among them – who believe it is worth regarding the problem of aging as potentially soluble, just like any other ailment. That’s why the author has developed a program that aims to stop aging.

This program is called SENS: Strategies for Engineered Negligible Senescence.

In the upcoming blinks, we’ll see how this strategy could help prevent mitochondrial mutations by clearing up the junk that plagues human cells. This junk includes disease-promoting proteins called AGEs and death-resistant “zombie cells.” We’ll also see how these steps can promote healthy cell loss as well as prevent DNA mutation, which leads to aging.

The author’s program does face some challenges, however: there are concerns about insufficient funding to properly develop the technology and conduct the research that is needed to stop people from aging.

But if funding does come through, he predicts – with a 50 percent certainty – that it will be possible for us to stop people from dying of old age.

Most scientists agree that aging is inevitable. However, the bodily damage that causes aging may be reparable.

Normally, prevention is better than cure. Preventing aging, however, might be too complex.

When we’re presented with a problem, there are generally two paths to explore when looking for a solution: prevention or cure. In the field of medicine, most problems are solved by offering a cure rather than prevention. This approach, however, has major drawbacks.

For example, if someone has heart disease or diabetes, they can obtain medication to help cure their ailments without ever finding out what caused the problem in the first place.

Mitochondrial mutation plays a huge part in aging and there might be ways to fix that.

So, what exactly are mitochondria? They’re commonly referred to as the “power plants of the cells,” because they produce the energy we need to live. But you only need to learn a little about power plants to know that energy production usually comes with nasty side effects.

In our bodies, one of these is free radicals.

The junk found both in and outside of cells is another treatable contributor to aging.

Just like a household, cells produce waste. And although cells recycle this waste in a better and more efficient way than most households, there is still leftover junk that can cause damage.

Part of this waste product is called lipofuscin, which the cells recycle via lysosomes.

By changing processes in our body we could stop cell loss and mutation, the main causes of cancer.

A central cause of aging is the gradual loss of cells. So it only makes sense that creating new ones would be a great way to fix this problem. And while there is a way to do this, politics and questions of morality are standing in the way.

For instance, one method involves stem cells. While we all contain adult stem cells, only embryonic stems cells can be used to produce new cells in our body. In fact, embryonic stem cells can be turned into any cell, including heart, lung and muscle cells.

AGE’s and “zombie cells” could be treated with drugs or enzymes to stop their aging.

If you’ve ever eaten meat that has been browned or blackened, then chances are you’ve eaten advanced glycation endproducts (AGEs) as well. But even if you haven’t, the same process that blackened the meat is also happening naturally in your body.

AGEs are the result of a complex chemical process where sugars and other substances bind to proteins. These AGEs accumulate in your cells, decreasing their functionality, and can lead to disease and early death.

The current therapies for humans aren’t perfect for humans, but they are a good starting point.

As we’ve seen, many of the first steps toward fighting aging have already been taken. But despite this fact, those at work on this issue are still in the minority.

This is why the author has come up with a plan to convince the majority. It’s called the robust mouse rejuvenation (RMR).

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Worum geht es in Ending Aging?

Ending Aging (2007) puts forward a fascinating theory about how science may allow human beings to slow the hands of time and, therefore, the process of aging. Learn what happens in our bodies that leads to aging, disease and cancer – and how modern science might be able to put an end to these problems once and for all.

Bestes Zitat aus Ending Aging

There is no ticking time bomb – just the accumulation of damage.

—Aubrey de Grey

Wer Ending Aging lesen sollte

Students of gerontology
Anyone hoping to prolong their life
Biologists interested in the experimental science of aging

Über den Autor

Aubrey de Grey, PhD, is chief science officer and chairman of the Methuselah Foundation. As a biomedical gerontologist, he is one of the most active scientists in the fight to stop aging. He developed the SENS program to stop aging. Currently, he organizes conferences and workshops to promote further research.

Michael Rae is Dr. de Grey’s research assistant. He was a board member of the Calorie Restriction Society and a major contributor to their how-to guide. He is also assisted with a partner study that tries to determine how calorie restriction might be feasible for humans.

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